articleTop 1% cited
Recent Advances in the Total Synthesis of Piperidine and Pyrrolidine Natural Alkaloids with Ring‐Closing Metathesis as a Key Step
European Journal of Organic Chemistry · 2003 · Vol. 2003(19) · pp. 3693–3712
François‐Xavier Felpin✉(Centre National de la Recherche Scientifique)Jacques Lebreton(Centre National de la Recherche Scientifique)
Abstract
Abstract This microreview focuses on recent applications of the ring‐closing metathesis reaction (RCM) to construct piperidine and pyrrolidine cores for the total synthesis of natural alkaloids. The most recent examples are described, from simple piperidine alkaloids to complex pentacyclic structures such as (+)‐tabersonine. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
Synthetic Organic Chemistry MethodsChemical Synthesis and AnalysisCarbohydrate Chemistry and SynthesisPiperidinePyrrolidineChemistryRing-closing metathesisTotal synthesisMetathesisRing (chemistry)Salt metathesis reactionStereochemistryOrganic chemistry
Funding
- Centre National de la Recherche Scientifique
Citations
436
FWCI
13.02
field-weighted impact
References
98
Percentile
100%
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Citations per year
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References
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Recent advances in olefin metathesis and its application in organic synthesis
Tetrahedron · 1998 · 2,091 citations
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Stereoselective Synthesis of Piperidines
Synthesis · 2000 · 376 citations
Macrocycles by Ring-Closing Metathesis
Synthesis · 1997 · 306 citations
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Recent Advances in the Total Synthesis of Piperidine and Pyrrolidine Natural Alkaloids with Ring‐Closing Metathesis as a Key Step
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