articleTop 1% cited
A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
Acta Neuropathologica · 1994 · Vol. 87(6) · pp. 554–567
F. Braak✉(Goethe University Frankfurt)Heiko Braak(Goethe University Frankfurt)Eva‐Maria Mandelkow(Max Planck Unit for Structural Molecular Biology)
Alzheimer's disease research and treatmentsS100 Proteins and AnnexinsNeurogenesis and neuroplasticity mechanismsSomaNeuropilNeurofilamentBiologyNeurofibrillary tangleAxonImmunostainingAnatomyCytoskeletonNeuroscience
MeSH terms
AdultAgedAged, 80 and overAlzheimer DiseaseCytoskeletonFemaleHumansImmunologic TechniquesMaleMiddle AgedNerve NetPhosphorylationSilverStaining and LabelingTemporal Lobe
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References
Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: A third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques
Neuroscience Letters · 1986 · 429 citations
Neuropathological stageing of Alzheimer-related changes
Acta Neuropathologica · 1991 · 16,076 citations
Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease
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