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Perioperative Single Dose Systemic Dexamethasone for Postoperative Pain

Anesthesiology · 2011 · Vol. 115(3) · pp. 575–588

Gildàsio S. De Oliveira✉(Northwestern University)Marcela Almeida(University of Chicago)Honorio T. Benzon(Northwestern University)Robert J. McCarthy(Northwestern University)

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Abstract

Dexamethasone at doses more than 0.1 mg/kg is an effective adjunct in multimodal strategies to reduce postoperative pain and opioid consumption after surgery. The preoperative administration of the drug produces less variation of effects on pain outcomes.

Nausea and vomiting management Anesthesia and Pain Management Anesthesia and Sedative AgentsMedicineDexamethasoneAnalgesicAnesthesiaPlaceboPerioperativeVomitingNauseaPostoperative nausea and vomitingOpioid

MeSH terms

Analgesics, OpioidAnti-Inflammatory AgentsChronic DiseaseData Interpretation, StatisticalDexamethasoneDose-Response Relationship, DrugHumansMovementPain, PostoperativePostoperative PainPatient DischargeRestTime FactorsReproducibility of ResultsRandomized Controlled Trials as Topic

Citations

737

FWCI

33.60

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

Guidelines for Perioperative Care for Pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS<sup>®</sup>) Society Recommendations