articleTop 10% cited
Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia
Leukemia · 2004 · Vol. 18(4) · pp. 676–684
Chihaya Imai✉(St. Jude Children's Research Hospital)Keichiro Mihara(St. Jude Children's Research Hospital)Martin Andreánsky(St. Jude Children's Research Hospital)I. Nicholson(Women's and Children's Hospital)C‐H Pui(University of Tennessee Health Science Center)Terrence L. Geiger(St. Jude Children's Research Hospital)Dario Campana(St. Jude Children's Research Hospital)
CAR-T cell therapy researchImmune Cell Function and InteractionImmunotherapy and Immune ResponsesCD19ReceptorBiologyChimeric antigen receptorCancer researchLeukemiaImmunologyCell biologyMolecular biologyT cell
MeSH terms
Burkitt LymphomaCytotoxicity Tests, ImmunologicHumansImmunoglobulin Variable RegionImmunotherapyRecombinant Fusion ProteinsT-LymphocytesTransduction, GeneticAntigens, CDCD8 AntigensCD3 ComplexProtein Structure, TertiaryReceptors, Nerve Growth FactorReceptors, Tumor Necrosis FactorImmunoconjugates
Funding
- American Cancer Society
- American Lebanese Syrian Associated Charities
Citations
811
FWCI
5.94
field-weighted impact
References
63
Percentile
97%
vs. same field & year
Citations per year
Cited by
CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia
Science Translational Medicine · 2013 · 2,062 citations
Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety
Leukemia · 2010 · 554 citations
A guide to cancer immunotherapy: from T cell basic science to clinical practice
Nature reviews. Immunology · 2020 · 4,024 citations
References
Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. European Group for Blood and Marrow Transplantation Working Party Chronic Leukemia [see comments]
Blood · 1995 · 1,968 citations
Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
Blood · 2003 · 1,588 citations
Characterization of EBV‐genome negative “null” and “T” cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non‐Hodgkin lymphoma
International Journal of Cancer · 1977 · 700 citations
Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)
International Journal of Cancer · 1976 · 2,431 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
