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Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

Oncogene · 2002 · Vol. 21(13) · pp. 2000–2008
Guilian NiuKenneth L. WrightMei HuangLanxi SongEric B. HauraJames TurksonShumin ZhangTianhong WangDominic SinibaldiDomenico CoppolaRichard HellerLee M. EllisJames G. KarrasJacqueline BrombergDrew M. PardollRichard JoveHua Yu
Cytokine Signaling Pathways and InteractionsAngiogenesis and VEGF in CancerProtein Tyrosine PhosphatasesBiologyAngiogenesisSTAT3Cancer researchProto-oncogene tyrosine-protein kinase SrcReceptor tyrosine kinaseVascular endothelial growth factorChromatin immunoprecipitationCell biologyMolecular biology

MeSH terms

AnimalsBase SequenceCell Line, TransformedCollagenDNA-Binding ProteinsDrug CombinationsHumansLamininLymphokinesNeoplasm TransplantationNeovascularization, PathologicPromoter Regions, GeneticProteoglycansTransfectionTumor Cells, Cultured
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