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The epidermal growth factor receptor family: Biology driving targeted therapeutics

Cellular and Molecular Life Sciences · 2008 · Vol. 65(10) · pp. 1566–1584
Matthew J. WieduwiltMark M. Moasser
HER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies ResearchPI3K/AKT/mTOR signaling in cancerErbBBiologyReceptor tyrosine kinaseReceptorEpidermal growth factor receptorGrowth factor receptor inhibitorEpidermal growth factorSignal transductionGrowth factor receptorCell biology

MeSH terms

AnimalsCell NucleusDiseaseMultigene FamilyHumansModels, BiologicalNeoplasmsSignal TransductionDrug Delivery SystemsGenes, erbBDrug Resistance, NeoplasmReceptor Cross-TalkActive Transport, Cell NucleusEmbryonic DevelopmentErbB Receptors
Citations
756
FWCI
7.56
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References
195
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98%
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References
The EGFR family and its ligands in human cancer
European Journal of Cancer · 2001 · 1,573 citations
Untangling the ErbB signalling network
Nature Reviews Molecular Cell Biology · 2001 · 6,890 citations
The deaf and the dumb: the biology of ErbB-2 and ErbB-3
Experimental Cell Research · 2003 · 588 citations
ERBB receptors and cancer: the complexity of targeted inhibitors
Nature reviews. Cancer · 2005 · 3,292 citations
Neuregulin 1 and Susceptibility to Schizophrenia
The American Journal of Human Genetics · 2002 · 1,659 citations
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