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Clinical trial: the effects of a trans‐galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome
Alimentary Pharmacology & Therapeutics · 2008 · Vol. 29(5) · pp. 508–518
D. B. A. Silk✉(Imperial College Healthcare NHS Trust)Andrew M. Davis(Central Middlesex Hospital)Jelena Vulevic(University of Reading)George Tzortzis(Clasado BioSciences (United Kingdom))Glenn R. Gibson(University of Reading)
Abstract
The galactooligosaccharide acted as a prebiotic in specifically stimulating gut bifidobacteria in IBS patients and is effective in alleviating symptoms. These findings suggest that the prebiotic has potential as a therapeutic agent in IBS.
Gastrointestinal motility and disordersGut microbiota and healthInfant Health and DevelopmentPrebioticIrritable bowel syndromeMedicineFlatulenceGastroenterologyBloatingInternal medicinePlaceboCrossover studyRandomized controlled trial
MeSH terms
AdultAgedBifidobacteriumFecesFemaleHumansMaleMiddle AgedOligosaccharidesQuality of LifeStatistics as TopicColony Count, MicrobialTreatment OutcomeProbioticsIrritable Bowel Syndrome
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