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Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute <i>Campylobacter</i> enteritis and in post-dysenteric irritable bowel syndrome

Gut · 2000 · Vol. 47(6) · pp. 804–811

Robert E. Spiller✉(Nottingham General Hospital)D Jenkins(University of Nottingham)J P Thornley(Nottingham City Hospital)J M Hebden(Nottingham General Hospital)T Wright(Nottingham City Hospital)M Skinner(University of Nottingham)K R Neal(Nottingham City Hospital)

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Abstract

Increased EC, T lymphocytes, and gut permeability are acute changes following Campylobacter enteritis which can persist for more than a year and may contribute to PD-IBS.

Microscopic Colitis Gastrointestinal motility and disorders Clostridium difficile and Clostridium perfringens researchIrritable bowel syndromeGastroenterologyEnteroendocrine cellMedicineEnteritisInternal medicineCampylobacterIntestinal permeabilityEndocrine systemBiology

MeSH terms

Acute DiseaseAdultAgedBiopsyCampylobacter InfectionsCell CountColonic Diseases, FunctionalEnteritisFemaleHumansIntestinal MucosaLife Change EventsLymphocytosisMaleMast Cells

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Cited by

Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. The confluence of increased permeability, inflammation, and pain in irritable bowel syndrome