Structure−Activity Relationships of Polymyxin Antibiotics

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVPerspectiveNEXTStructure−Activity Relationships of Polymyxin AntibioticsTony Velkov*†‡, Philip E. Thompson‡, Roger L. Nation§, and Jian Li*§View Author Information† School of Medicine, Deakin University, Pigdons Road, Geelong 3217, Victoria, Australia‡ Medicinal Chemistry and Drug Action§ Facility for Anti-infective Drug Development and Innovation, Drug Delivery, Disposition and Dynamics Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, Victoria, Australia*To whom correspondence should be addressed. For T.V.: phone, +61-3-9903 9539; fax, +61-3-9903 9582; e-mail, [email protected] or [email protected]. For J.L.: phone, +61-3-9903 9702; fax, +61-3-9903 9629; e-mail, [email protected]Cite this: J. Med. Chem. 2010, 53, 5, 1898–1916Publication Date (Web):October 29, 2009Publication History Received7 July 2009Published online29 October 2009Published inissue 11 March 2010https://pubs.acs.org/doi/10.1021/jm900999hhttps://doi.org/10.1021/jm900999hreview-articleACS PublicationsCopyright © 2009 American Chemical SocietyRequest reuse permissionsArticle Views8703Altmetric-Citations568LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Acyls,Antimicrobial activity,Hydrophobicity,Lipids,Peptides and proteins Get e-Alerts