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The redox chemistry of the Alzheimer's disease amyloid β peptide

Biochimica et Biophysica Acta (BBA) - Biomembranes · 2007 · Vol. 1768(8) · pp. 1976–1990
Danielle G. SmithRoberto CappaiKevin J. Barnham
Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesBiochemical effects in animalsChemistryOxidative stressReactive oxygen speciesLipid peroxidationRedoxBiochemistryOxidative phosphorylationPeptidePro-oxidantAmyloid (mycology)

MeSH terms

Alzheimer DiseaseAnimalsAntioxidantsChelating AgentsCurcuminDNAEnzyme InhibitorsHumansMetalsOxidation-ReductionOxygenOxygen ConsumptionPeptidesPlant ExtractsTyrosine

Funding

  • Australian Research Council
  • National Health and Medical Research Council
Citations
592
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21.05
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References
227
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References
Copper biochemistry and molecular biology
American Journal of Clinical Nutrition · 1996 · 1,407 citations
Characterization of Copper Interactions with Alzheimer Amyloid β Peptides
Journal of Neurochemistry · 2000 · 636 citations
Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
Biochemical and Biophysical Research Communications · 1984 · 1,668 citations
Oxidation of methionyl residues in proteins: Tools, targets, and reversal
Free Radical Biology and Medicine · 1995 · 876 citations
Amyloid plaque core protein in Alzheimer disease and Down syndrome.
Proceedings of the National Academy of Sciences · 1985 · 4,412 citations
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The redox chemistry of the Alzheimer's disease amyloid β peptide · Scinovex