review Open AccessTop 1% cited
Beyond GWASs: Illuminating the Dark Road from Association to Function
The American Journal of Human Genetics · 2013 · Vol. 93(5) · pp. 779–797
Stacey L. Edwards✉(University of Queensland)Jonathan Beesley(QIMR Berghofer Medical Research Institute)Juliet D. French(University of Queensland)Alison M. Dunning(University of Cambridge)
Genetic Associations and EpidemiologyRNA modifications and cancerRNA Research and SplicingGenome-wide association studyGenetic associationBiologyComputational biologyGeneticsSingle-nucleotide polymorphismEpigeneticsGeneGenotype
MeSH terms
AnimalsChromosome MappingHumansNeoplasmsPhenotypeRisk FactorsComputational BiologyGenetic Predisposition to DiseasePolymorphism, Single NucleotideRNA, UntranslatedEpigenesis, GeneticGenome-Wide Association StudyGenetic Loci
Funding
- Wellcome Trust
Citations
844
FWCI
45.91
field-weighted impact
References
123
Percentile
100%
vs. same field & year
Citations per year
Cited by
Non-coding genetic variants in human disease: Figure 1.
Human Molecular Genetics · 2015 · 646 citations
Benefits and limitations of genome-wide association studies
Nature Reviews Genetics · 2019 · 2,137 citations
Functional mapping and annotation of genetic associations with FUMA
Nature Communications · 2017 · 4,347 citations
The Post-GWAS Era: From Association to Function
The American Journal of Human Genetics · 2018 · 884 citations
Rare-Variant Association Analysis: Study Designs and Statistical Tests
The American Journal of Human Genetics · 2014 · 1,100 citations
References
Finding the missing heritability of complex diseases
Nature · 2009 · 8,468 citations
Genome editing with engineered zinc finger nucleases
Nature Reviews Genetics · 2010 · 2,248 citations
The language of covalent histone modifications
Nature · 2000 · 8,530 citations
DNA methylation and human disease
Nature Reviews Genetics · 2005 · 2,869 citations
Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements
Genome Research · 2006 · 1,231 citations
High-Resolution Profiling of Histone Methylations in the Human Genome
Cell · 2007 · 6,869 citations
Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS
PLoS Genetics · 2010 · 1,408 citations
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Nature · 2012 · 8,404 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.