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Growth hormone treatment of adults withgrowth hormone deficiency: results of a 13‐month placebo controlled cross‐over study

Clinical Endocrinology · 1992 · Vol. 36(1) · pp. 45–52

Helen M. Whitehead✉(Royal Victoria Hospital)C Boreham(Queen's University Belfast)Edwin M. Mcllrath(Royal Victoria Hospital)B. Sheridan(Royal Victoria Hospital)Laurence Kennedy(Royal Victoria Hospital)A. Brew Atkinson(Royal Victoria Hospital)David R. Madden(Royal Victoria Hospital)

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Abstract

GH alters the body composition of growth hormone deficient adults and leads to improved exercise capacity; alkaline phosphatase activity increases but without a change in spinal bone density, and carbohydrate tolerance remains unaltered.

Growth Hormone and Insulin-like Growth Factors Diet and metabolism studies Muscle metabolism and nutritionPlaceboEndocrinologyInternal medicineLean body massMedicineGrowth hormone treatmentVO2 maxGrowth hormoneHormoneGrowth hormone deficiency

MeSH terms

AdultAlkaline PhosphataseBody CompositionDouble-Blind MethodFemaleGrowth DisordersHumansMaleMiddle AgedOxygen ConsumptionRecombinant ProteinsGrowth Hormone

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The growth hormone deficiency syndrome in adults