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Acute Physiology and Chronic Health Evaluation (APACHE) IV: Hospital mortality assessment for today’s critically ill patients*

Critical Care Medicine · 2006 · Vol. 34(5) · pp. 1297–1310

Jack E. Zimmerman✉(Dynamic Structures and Materials (United States))Andrew A. Kramer(Dynamic Structures and Materials (United States))Douglas McNair(Dynamic Structures and Materials (United States))Fern M. Malila(Dynamic Structures and Materials (United States))

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Abstract

APACHE IV predictions of hospital mortality have good discrimination and calibration and should be useful for benchmarking performance in U.S. ICUs. The accuracy of predictive models is dynamic and should be periodically retested. When accuracy deteriorates they should be revised and updated.

Sepsis Diagnosis and Treatment Cardiac, Anesthesia and Surgical Outcomes Hemodynamic Monitoring and TherapyMedicineAPACHE IILogistic regressionReceiver operating characteristicIntensive care unitIntensive careCritically illEmergency medicineObservational studyIntensive care medicine

MeSH terms

AdultAgedAged, 80 and overCalibrationFemaleHumansIntensive Care UnitsMaleMiddle AgedPredictive Value of TestsROC CurveUnited StatesReproducibility of ResultsCohort StudiesMultivariate Analysis

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Changes in hospital mortality for United States intensive care unit admissions from 1988 to 2012