articleTop 1% cited
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
Nature Protocols · 2007 · Vol. 2(9) · pp. 2212–2221
F. Niesen✉(Genomics (United Kingdom))H. Berglund(Karolinska Institutet)Masoud Vedadi(Structural Genomics Consortium)
Molecular Biology Techniques and Applicationsthermodynamics and calorimetric analysesProtein purification and stabilityFluorescenceNucleic acidFluorescence spectroscopyChemistryLigand (biochemistry)BiophysicsPeptideChromatographyAnalytical Chemistry (journal)Biochemistry
MeSH terms
AnimalsCitrate (si)-SynthaseEnzyme StabilityFluorescent DyesFluorometryLigandsProtein ConformationProtein DenaturationSwineTemperaturePolymerase Chain ReactionProtein FoldingOxaloacetic Acid
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References
Using circular dichroism spectra to estimate protein secondary structure
Nature Protocols · 2006 · 3,890 citations
How to measure and predict the molar absorption coefficient of a protein
Protein Science · 1995 · 3,888 citations
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