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Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: A randomized, controlled trial
Arthritis & Rheumatism · 2004 · Vol. 50(11) · pp. 3432–3443
E. William St. Clair✉(Duke Medical Center)Désirée van der Heijde(Maastricht University Medical Centre)Josef S Smolen(Medical University of Vienna)Ravinder N. Maini(British Society for Rheumatology)Joan M. Bathon(Johns Hopkins University)Paul Emery(University of Leeds)Edward Keystone(Mount Sinai Hospital)Michael Schiff(Denver Arthritis Clinic)Joachim R. Kalden(Fraunhofer Institute for Cell Therapy and Immunology)Ben WangKimberly L. DeWoodyRoberta WeissDaniel L. BakerActive‐Controlled Study of Patients Receiving Infliximab for the Treatment of Rheumatoid Arthritis of Early Onset Study Group
Abstract
For patients with active RA in its early stages, combination therapy with MTX and infliximab provides greater clinical, radiographic, and functional benefits than treatment with MTX alone.
Rheumatoid Arthritis Research and TherapiesChronic Lymphocytic Leukemia ResearchAutoimmune and Inflammatory Disorders ResearchInfliximabMedicineRheumatoid arthritisMethotrexatePlaceboInternal medicineGastroenterologyArthritisRheumatologySurgery
MeSH terms
InfliximabAdultAntibodiesAntibodies, MonoclonalArthritis, RheumatoidArthrographyDrug Therapy, CombinationFemaleHumansMaleMethotrexateMiddle AgedPatient DropoutsAutoimmunityTreatment Outcome
Citations
1,165
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53.47
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References
42
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References
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