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Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: A randomized, controlled trial

Arthritis & Rheumatism · 2004 · Vol. 50(11) · pp. 3432–3443
E. William St. ClairDésirée van der HeijdeJosef S SmolenRavinder N. MainiJoan M. BathonPaul EmeryEdward KeystoneMichael SchiffJoachim R. KaldenBen WangKimberly L. DeWoodyRoberta WeissDaniel L. BakerActive‐Controlled Study of Patients Receiving Infliximab for the Treatment of Rheumatoid Arthritis of Early Onset Study Group

Abstract

For patients with active RA in its early stages, combination therapy with MTX and infliximab provides greater clinical, radiographic, and functional benefits than treatment with MTX alone.

Rheumatoid Arthritis Research and TherapiesChronic Lymphocytic Leukemia ResearchAutoimmune and Inflammatory Disorders ResearchInfliximabMedicineRheumatoid arthritisMethotrexatePlaceboInternal medicineGastroenterologyArthritisRheumatologySurgery

MeSH terms

InfliximabAdultAntibodiesAntibodies, MonoclonalArthritis, RheumatoidArthrographyDrug Therapy, CombinationFemaleHumansMaleMethotrexateMiddle AgedPatient DropoutsAutoimmunityTreatment Outcome
Citations
1,165
FWCI
53.47
field-weighted impact
References
42
Percentile
100%
vs. same field & year
Citations per year
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Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: A randomized, controlled trial · Scinovex