article Open AccessTop 1% cited
Sleep Duration and Biomarkers of Inflammation
SLEEP · 2009 · Vol. 32(2) · pp. 200–204
Sanjay R. Patel✉(Case Western Reserve University)Xiaobei Zhu(Case Western Reserve University)Amy Storfer‐Isser(Case Western Reserve University)Reena Mehra(Case Western Reserve University)Nancy S. Jenny(University of Vermont)Russell P. Tracy(University of Vermont)Susan Redline(Case Western Reserve University)
Abstract
Increases in habitual sleep durations are associated with elevations in CRP and IL-6 while reduced PSG sleep duration is associated with elevated TNFa levels. Activation of pro-inflammatory pathways may represent a mechanism by which extreme sleep habits affect health.
Sleep and related disordersCircadian rhythm and melatoninSleep and Wakefulness ResearchMedicinePolysomnographySleep (system call)Internal medicineBlood samplingInflammationMorningSleep apneaInterleukin 6Cohort
MeSH terms
AdultC-Reactive ProteinFemaleHealth SurveysHumansDisorders of Excessive SomnolenceInterleukin-1Longitudinal StudiesMaleMiddle AgedObesityPhenotypeSleep DeprivationTumor Necrosis Factor-alphaCohort Studies
Citations
598
FWCI
16.03
field-weighted impact
References
24
Percentile
99%
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Citations per year
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References
A New Method for Measuring Daytime Sleepiness: The Epworth Sleepiness Scale
SLEEP · 1991 · 16,956 citations
Elevated Inflammatory Markers in Response to Prolonged Sleep Restriction Are Associated With Increased Pain Experience in Healthy Volunteers
SLEEP · 2007 · 597 citations
Adverse Effects of Modest Sleep Restriction on Sleepiness, Performance, and Inflammatory Cytokines
The Journal of Clinical Endocrinology & Metabolism · 2004 · 1,048 citations
A Prospective Study of Sleep Duration and Coronary Heart Disease in Women
Archives of Internal Medicine · 2003 · 1,157 citations
C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus
JAMA · 2001 · 4,400 citations
Mortality Associated With Sleep Duration and Insomnia
Archives of General Psychiatry · 2002 · 1,616 citations
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