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Elevated Inflammatory Markers in Response to Prolonged Sleep Restriction Are Associated With Increased Pain Experience in Healthy Volunteers

SLEEP · 2007 · Vol. 30(9) · pp. 1145–1152
Monika HaackElsa SanchezJanet Mullington

Abstract

Insufficient sleep quantity may facilitate and/or exacerbate pain through elevations of IL-6. In disorders where sleep disturbances are common, insufficient sleep quantity itself may establish and maintain its co-occurrence with pain and increased inflammation.

Sleep and related disordersFibromyalgia and Chronic Fatigue Syndrome ResearchExercise and Physiological ResponsesMedicineSleep restrictionInternal medicineSleep (system call)InflammationEndocrinologyMoodUrineSleep deprivationCircadian rhythm

MeSH terms

AdultC-Reactive ProteinFemaleHealth StatusHumansInflammationMalePainPain MeasurementReference ValuesSleep DeprivationProstaglandin D2DinoprostoneBiomarkersInterleukin-6
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