article Open AccessTop 1% cited
Elevated Inflammatory Markers in Response to Prolonged Sleep Restriction Are Associated With Increased Pain Experience in Healthy Volunteers
SLEEP · 2007 · Vol. 30(9) · pp. 1145–1152
Monika Haack✉(Beth Israel Deaconess Medical Center)Elsa Sanchez(Beth Israel Deaconess Medical Center)Janet Mullington(Beth Israel Deaconess Medical Center)
Abstract
Insufficient sleep quantity may facilitate and/or exacerbate pain through elevations of IL-6. In disorders where sleep disturbances are common, insufficient sleep quantity itself may establish and maintain its co-occurrence with pain and increased inflammation.
Sleep and related disordersFibromyalgia and Chronic Fatigue Syndrome ResearchExercise and Physiological ResponsesMedicineSleep restrictionInternal medicineSleep (system call)InflammationEndocrinologyMoodUrineSleep deprivationCircadian rhythm
MeSH terms
AdultC-Reactive ProteinFemaleHealth StatusHumansInflammationMalePainPain MeasurementReference ValuesSleep DeprivationProstaglandin D2DinoprostoneBiomarkersInterleukin-6
Citations
597
FWCI
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field-weighted impact
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45
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99%
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References
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The Journal of Clinical Endocrinology & Metabolism · 2004 · 1,048 citations
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