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Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

Acta Neuropathologica · 2014 · Vol. 128(6) · pp. 805–820

Staffan Holmqvist✉(Lund University)Oldriska Chutna(Lund University)Luc Bousset(Centre National de la Recherche Scientifique)Patrick Aldrin-Kirk(Lund University)Wen Li(Lund University)Tomas Björklund(Lund University)Zhan‐You Wang(Northeastern University)Laurent Roybon(Lund University)Ronald Melki(Laboratoire d'Enzymologie et Biochimie Structurales)Jiayi Li(Northeastern University)

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Parkinson's Disease Mechanisms and Treatments Neurological diseases and metabolism Nerve injury and regenerationDorsal motor nucleusAlpha-synucleinLewy bodyAxoplasmic transportNeuriteNeuroscienceBiologyPathologyParkinson's diseaseBrainstem

MeSH terms

AnimalsAxonal TransportBrainDisease Models, AnimalHumansParkinson DiseaseRecombinant ProteinsVagus NerveRats, Sprague-DawleyDisease ProgressionGastrointestinal TractCell Line, Tumoralpha-Synuclein

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897

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29.73

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Colonic bacterial composition in Parkinson's disease