articleTop 10% cited
Breaking The Cycle: Treatment Strategies for 163 Cases of Recurrent Clostridium Difficile Disease
The American Journal of Gastroenterology · 2002 · Vol. 97(7) · pp. 1769–1775
Lynne V. McFarland(University of Washington)Gary W. Elmer(University of Washington)Christina M. Surawicz✉(University of Washington)
Abstract
These data show that tapered or pulsed dosing regimens of vancomycin may result in a significantly better cure of RCDD. The persistence of C. difficile spores suggests that additional strategies to restore the normal colonic microflora may also be beneficial.
Clostridium difficile and Clostridium perfringens researchMicroscopic ColitisNosocomial Infections in ICUMedicineMetronidazoleVancomycinClostridium difficileInternal medicinePlaceboDosingClindamycinSurgeryGastroenterology
MeSH terms
AdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsEnterocolitis, PseudomembranousFemaleHumansMaleMetronidazoleMiddle AgedRecurrenceRemission InductionRisk FactorsVancomycin
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