review Open AccessTop 1% cited

Intestinal barrier function: Molecular regulation and disease pathogenesis

Journal of Allergy and Clinical Immunology · 2009 · Vol. 124(1) · pp. 3–20

Katherine Groschwitz✉Simon P. Hogan(Cincinnati Children's Hospital Medical Center)

Barrier Structure and Function Studies Gut microbiota and health Digestive system and related healthAdherens junctionBarrier functionTight junctionCell biologyIntestinal epitheliumBiologySeptate junctionsCell junctionTransmembrane proteinEpithelium

MeSH terms

HumansIntercellular JunctionsIntestinal MucosaInflammatory Bowel Diseases

Citations

1,689

FWCI

29.48

field-weighted impact

References

282

Percentile

100%

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Citations per year

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References

Multifunctional strands in tight junctions

Nature Reviews Molecular Cell Biology · 2001 · 2,465 citations

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

Nature Immunology · 2001 · 2,508 citations

Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process

American Journal of Physiology-Gastrointestinal and Liver Physiology · 1990 · 550 citations

Claudins create charge-selective channels in the paracellular pathway between epithelial cells

American Journal of Physiology-Cell Physiology · 2002 · 541 citations

Crosstalk of tight junction components with signaling pathways

Biochimica et Biophysica Acta (BBA) - Biomembranes · 2007 · 744 citations

Structure and function of claudins

Biochimica et Biophysica Acta (BBA) - Biomembranes · 2007 · 811 citations

JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA

The Journal of Cell Biology · 1963 · 3,608 citations

Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin

The Journal of Cell Biology · 1998 · 2,056 citations

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