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Behavioral and neurochemical effects following neurotoxic lesions of a major cholinergic input to the cerebral cortex in the rat1
Pharmacology Biochemistry and Behavior · 1983 · Vol. 18(6) · pp. 973–981
Charles Flicker✉(New York University)Richard DeanDorothy L. WatkinsS FISHERRaymond T. Bartus(New York University)
Neuroscience and Neuropharmacology ResearchCholinesterase and Neurodegenerative DiseasesMemory and Neural MechanismsGlobus pallidusIbotenic acidNucleus basalisNeuroscienceBasal gangliaCerebral cortexCholine acetyltransferaseLesionNeurochemicalPsychology
MeSH terms
AcetylcholineAcetylcholinesteraseAnimalsBrainCerebral CortexCholine O-AcetyltransferaseDenervationGlobus PallidusHistocytochemistryIbotenic AcidKineticsMaleMotor ActivityNeuronsOxazoles
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373
FWCI
9.77
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48
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99%
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Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats
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References
Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis
Annals of Neurology · 1981 · 1,736 citations
Human Memory and the Cholinergic System
Archives of Neurology · 1974 · 1,396 citations
A rapid radiochemical method for the determination of choline acetyltransferase
Journal of Neurochemistry · 1975 · 2,401 citations
THE ASCENDING CHOLINERGIC RETICULAR SYSTEM: NEOCORTICAL, OLFACTORY AND SUBCORTICAL PROJECTIONS
Brain · 1967 · 1,118 citations
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