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Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting*

Critical Care Medicine · 2006 · Vol. 34(6) · pp. 1608–1616
Colleen G. KochLiang LiAndra I. DuncanTomislav MihaljevićDelos M. CosgroveFloyd D. LoopNorman J. StarrEugene H. Blackstone

Abstract

Perioperative red blood cell transfusion is the single factor most reliably associated with increased risk of postoperative morbid events after isolated coronary artery bypass grafting. Each unit of red cells transfused is associated with incrementally increased risk for adverse outcome.

Blood transfusion and managementCardiac and Coronary Surgery TechniquesHyperglycemia and glycemic control in critically ill and hospitalized patientsMedicinePerioperativePacked red blood cellsBlood transfusionOdds ratioInternal medicineArteryCardiologyIntensive care unitConfidence interval

MeSH terms

AgedCoronary Artery BypassFemaleFollow-Up StudiesHumansMaleMiddle AgedMorbidityPostoperative ComplicationsProspective StudiesRisk FactorsSurvival RateBlood Component TransfusionHospital MortalityMyocardial Ischemia
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944
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22.60
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55
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100%
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References
Effect of blood transfusion on long-term survival after cardiac operation
The Annals of Thoracic Surgery · 2002 · 695 citations
Blood Transfusion, Independent of Shock Severity, Is Associated with Worse Outcome in Trauma
The Journal of Trauma: Injury, Infection, and Critical Care · 2003 · 619 citations
Blood Transfusion
Archives of Surgery · 1997 · 565 citations
The Systemic Inflammatory Response to Cardiac Surgery
Anesthesiology · 2002 · 862 citations
Guidelines for the clinical use of red cell transfusions
British Journal of Haematology · 2001 · 407 citations
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