reviewTop 1% cited
The P-loop — a common motif in ATP- and GTP-binding proteins
Trends in Biochemical Sciences · 1990 · Vol. 15(11) · pp. 430–434
Matti Saraste✉Peter R. Sibbald(European Molecular Biology Laboratory)Alfred Wittinghofer(Max Planck Institute of Molecular Physiology)
Enzyme Structure and FunctionProtein Structure and DynamicsProtein Kinase Regulation and GTPase SignalingGTP'Binding siteBiochemistrySequence motifThreonineSerineBiologyLoop (graph theory)Structural motifChemistry
MeSH terms
Adenosine TriphosphateAmino Acid SequenceAnimalsHumansMolecular Sequence DataMutationProtein ConformationProteinsSequence Homology, Nucleic AcidGTP-Binding Proteins
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References
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.
The EMBO Journal · 1982 · 5,305 citations
<i>ras</i> GENES
Annual Review of Biochemistry · 1987 · 3,877 citations
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