reviewTop 1% cited
Mitochondria as regulators of apoptosis: doubt no more
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 1998 · Vol. 1366(1-2) · pp. 151–165
Santos A. Susín(Centre National de la Recherche Scientifique)Naoufal Zamzami(Centre National de la Recherche Scientifique)Guido Kroemer✉(Centre National de la Recherche Scientifique)
Cell death mechanisms and regulationMitochondrial Function and PathologyATP Synthase and ATPases ResearchCell biologyMitochondrionApoptosisBiologyMitochondrial permeability transition poreMitochondrial apoptosis-induced channelIntermembrane spaceProgrammed cell deathInner membraneIntrinsic apoptosis
MeSH terms
AnimalsCytochrome c GroupIntracellular MembranesMembrane PotentialsMitochondriaPermeabilityCalcium ChannelsSignal TransductionCell DeathApoptosisProto-Oncogene Proteins c-bcl-2
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References
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The EMBO Journal · 1998 · 2,997 citations
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Neuron · 1995 · 1,882 citations
Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells
Journal of Neuroscience Research · 1998 · 380 citations
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
The EMBO Journal · 1998 · 1,231 citations
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The Journal of Experimental Medicine · 1995 · 1,564 citations
Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis
The Journal of Experimental Medicine · 1997 · 1,859 citations
Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c
Cell · 1996 · 5,154 citations
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