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Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine
Neuropsychopharmacology · 1996 · Vol. 14(2) · pp. 87–96
Frank P. Bymaster✉(Eli Lilly (United States))David O. Calligaro(Eli Lilly (United States))Julie F. Falcone(Eli Lilly (United States))Richard D Marsh(Eli Lilly (United States))Nicholas Moore(Eli Lilly (United Kingdom))N.C. Tye(Eli Lilly (United Kingdom))Philip Seeman(Eli Lilly (United Kingdom))David T. Wong(University of Toronto)
Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and SignalingNeurotransmitter Receptor Influence on BehaviorOlanzapineClozapinePharmacologyAtypical antipsychoticHaloperidolAntipsychoticChemistry5-HT receptor5-HT1 receptorReceptor
MeSH terms
OlanzapineAnimalsBenzodiazepinesCattleCricetinaeHumansMaleMyocardiumPirenzepineRadioligand AssayReceptors, AdrenergicReceptors, DopamineReceptors, Histamine H1Receptors, MuscarinicReceptors, Serotonin
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Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
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Archives of General Psychiatry · 1988 · 4,110 citations
Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.
Journal of Pharmacology and Experimental Therapeutics · 1989 · 1,350 citations
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