article Open AccessTop 1% cited
Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
Immunity · 2014 · Vol. 40(1) · pp. 128–139
Nagendra Singh✉(Augusta University)Ashish Gurav(Augusta University)Sathish Sivaprakasam(Augusta University)Evan Brady(Augusta University)Ravi N. Padia(Augusta University)Huidong Shi(Augusta University)Muthusamy Thangaraju(Augusta University)Puttur D. Prasad(Augusta University)Santhakumar Manicassamy(Augusta University)David H. Munn(Augusta University)Jeffrey R. Lee(Charlie Norwood VA Medical Center)Stefan Offermanns(Max Planck Institute for Heart and Lung Research)Vadivel Ganapathy✉(Augusta University)
Gut microbiota and healthHelicobacter pylori-related gastroenterology studiesProbiotics and Fermented FoodsButyrateInflammationNiacinBiologyGut floraColorectal cancerReceptorColitisCancer researchImmunology
MeSH terms
AnimalsButyratesCell DifferentiationCells, CulturedColitisColonColonic NeoplasmsDendritic CellsDisease SusceptibilityEpithelial CellsLymphocyte ActivationMacrophagesMice, Inbred C57BLNiacinReceptors, Nicotinic
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2,217
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48
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References
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The ISME Journal · 2011 · 1,313 citations
Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces
Immunity · 2008 · 1,525 citations
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
Proceedings of the National Academy of Sciences · 2007 · 4,550 citations
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism
The Journal of Experimental Medicine · 2007 · 2,639 citations
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
The Journal of Experimental Medicine · 2007 · 1,845 citations
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