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Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

Developmental Cell · 2011 · Vol. 21(1) · pp. 92–101
Jean‐Claude MartinouRichard J. Youle
Mitochondrial Function and PathologyCell death mechanisms and regulationATP Synthase and ATPases ResearchBiologyMitochondrionIntermembrane spaceCell biologyMitochondrial fissionCaenorhabditis elegansMitochondrial apoptosis-induced channelMitochondrial intermembrane spaceCytosolOrganelle

MeSH terms

AnimalsCell MembraneHumansMitochondriaApoptosisProto-Oncogene Proteins c-bcl-2

Funding

  • National Institute of Neurological Disorders and Stroke
  • Core Research for Evolutional Science and Technology
Citations
1,343
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References
Mitochondrial Membrane Permeabilization in Cell Death
Physiological Reviews · 2007 · 3,546 citations
The BCL-2 protein family: opposing activities that mediate cell death
Nature Reviews Molecular Cell Biology · 2007 · 4,586 citations
Mitochondria and cell death: outer membrane permeabilization and beyond
Nature Reviews Molecular Cell Biology · 2010 · 2,483 citations
Mechanics of membrane fusion
Nature Structural & Molecular Biology · 2008 · 1,020 citations
Barrel-Stave Model or Toroidal Model? A Case Study on Melittin Pores
Biophysical Journal · 2001 · 1,091 citations
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