reviewTop 1% cited
The Regulation and Activities of the Multifunctional Serine/Threonine Kinase Akt/PKB
Experimental Cell Research · 1999 · Vol. 253(1) · pp. 210–229
Eugene Kandel(University of Illinois Chicago)Nissim Hay✉(University of Illinois Chicago)
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and CancerFOXO transcription factor regulationProtein kinase BAKT1BiologyAKT2PI3K/AKT/mTOR pathwayCell biologyPTENKinasemTORC2AKT3
MeSH terms
Cell Transformation, NeoplasticDiabetes MellitusEnzyme ActivationPhosphorylationProto-Oncogene ProteinsSignal TransductionProtein Serine-Threonine KinasesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akt
Citations
873
FWCI
19.14
field-weighted impact
References
202
Percentile
100%
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Citations per year
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References
Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation
Biochemical Journal · 1998 · 1,078 citations
Antiapoptotic Signalling by the Insulin-Like Growth Factor I Receptor, Phosphatidylinositol 3-Kinase, and Akt
Molecular and Cellular Biology · 1997 · 1,049 citations
Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway
Journal of Biological Chemistry · 1998 · 1,982 citations
The mRNA 5′ cap-binding protein eIF4E and control of cell growth
Current Opinion in Cell Biology · 1998 · 669 citations
Molecular alterations of the <i>AKT</i>2 oncogene in ovarian and breast carcinomas
International Journal of Cancer · 1995 · 836 citations
Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily
Genomics · 1998 · 353 citations
The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate
Journal of Biological Chemistry · 1998 · 3,080 citations
Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery
Cell · 1997 · 5,689 citations
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