reviewTop 1% cited
Analytical Strategies in Metabonomics
Journal of Proteome Research · 2006 · Vol. 6(2) · pp. 443–458
Eva M. Lenz✉(AstraZeneca (United Kingdom))Ian D. Wilson(AstraZeneca (United Kingdom))
Abstract
To perform metabonomics investigations, it is necessary to generate comprehensive metabolite profiles for complex samples such as biofluids and tissue/tissue extracts. Analytical technologies that can be used to achieve this aim are constantly evolving, and new developments are changing the way in which such profiles' metabolite profiles can be generated. Here, the utility of various analytical techniques for global metabolite profiling, such as, e.g., 1H NMR, MS, HPLC-MS, and GC-MS, are explored and compared.
Metabolomics and Mass Spectrometry StudiesAnalytical Chemistry and ChromatographyMass Spectrometry Techniques and ApplicationsMetaboliteMetabolite profilingMetabolomicsProfiling (computer programming)ChemistryComputational biologyChromatographyMetabolomeComputer scienceBiology
MeSH terms
Circadian RhythmFemaleHumansMaleMetabolismMagnetic Resonance SpectroscopyProteinsWater
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