article Open AccessTop 1% cited

Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes

Lara D. Veeken · 2001 · Vol. 40(2) · pp. 205–211

James Edwards✉(University College London)Geraldine Cambridge(University College London)

Abstract

Objectives. An open study of B‐lymphocyte depletion was undertaken in rheumatoid arthritis (RA) patients to test the hypothesis that B lymphocytes may be essential to disease perpetuation.

Rheumatoid Arthritis Research and Therapies Systemic Lupus Erythematosus Research Chronic Lymphocytic Leukemia ResearchMedicineRheumatoid arthritisProtocol (science)ImmunologyPathologyAlternative medicine

Funding

F. Hoffmann-La Roche
University College London Hospitals NHS Foundation Trust

Citations

517

FWCI

20.97

field-weighted impact

References

Percentile

100%

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Citations per year

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References

Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.

Journal of Clinical Oncology · 1998 · 2,755 citations

Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor ? monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis

Arthritis & Rheumatism · 1998 · 1,638 citations

American college of rheumatology preliminary definition of improvement in rheumatoid arthritis

Arthritis & Rheumatism · 1995 · 2,833 citations

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