articleTop 1% cited
Use of a Glutaric Acid Cocrystal to Improve Oral Bioavailability of a Low Solubility API
Pharmaceutical Research · 2006 · Vol. 23(8) · pp. 1888–1897
Daniel P. McNamara✉(Purdue Pharma (United States))S.L. Childs(Atlanta Research and Education Foundation)Jennifer Giordano(Purdue Pharma (United States))Anthony Iarriccio(Purdue Pharma (United States))James T. Cassidy(Purdue Pharma (United States))Manjunath S. Shet(Purdue Pharma (United States))Richard O. Mannion(Purdue Pharma (United States))Ed O'Donnell(Purdue Pharma (United States))Aeri Park(CACI International (United States))
Crystallography and molecular interactionsCrystallization and Solubility StudiesCrystal structures of chemical compoundsCocrystalDissolutionSolubilitySynthonCrystal engineeringChemistryBioavailabilityActive ingredientGlutaric acidAmorphous solid
MeSH terms
AnimalsBiological AvailabilityCalorimetry, Differential ScanningChemistry, PhysicalCrystallizationDogsDrug StabilityDrug StoragePharmaceutical PreparationsExcipientsGlutaratesHumidityHydrogen BondingModels, MolecularMolecular Conformation
Funding
- Purdue Pharma
Citations
685
FWCI
25.61
field-weighted impact
References
27
Percentile
100%
vs. same field & year
Citations per year
Cited by
Effects of Crystal Form on Solubility and Pharmacokinetics: A Crystal Engineering Case Study of Lamotrigine
Crystal Growth & Design · 2009 · 247 citations
Applying Hot-Stage Microscopy to Co-Crystal Screening: A Study of Nicotinamide with Seven Active Pharmaceutical Ingredients
Crystal Growth & Design · 2008 · 343 citations
Solubility Advantage of Amorphous Drugs and Pharmaceutical Cocrystals
Crystal Growth & Design · 2011 · 977 citations
Pharmaceutical Cocrystals and Their Physicochemical Properties
Crystal Growth & Design · 2009 · 1,459 citations
Solubility Advantage of Pharmaceutical Cocrystals
Crystal Growth & Design · 2009 · 824 citations
Fast Dissolving Curcumin Cocrystals
Crystal Growth & Design · 2011 · 246 citations
Synthesis and Structural Characterization of Cocrystals and Pharmaceutical Cocrystals: Mechanochemistry vs Slow Evaporation from Solution
Crystal Growth & Design · 2009 · 440 citations
Polymorphs, Salts, and Cocrystals: What’s in a Name?
Crystal Growth & Design · 2012 · 1,018 citations
References
A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability
Pharmaceutical Research · 1995 · 5,270 citations
Molecular Complexes of Homologous Alkanedicarboxylic Acids with Isonicotinamide: X-ray Crystal Structures, Hydrogen Bond Synthons, and Melting Point Alternation
Crystal Growth & Design · 2003 · 271 citations
Phase Solubility Diagrams of Cocrystals Are Explained by Solubility Product and Solution Complexation
Crystal Growth & Design · 2005 · 308 citations
Supramolecular Synthons in Crystal Engineering—A New Organic Synthesis
Angewandte Chemie International Edition in English · 1995 · 4,793 citations
Related articles
Pharmaceutical Cocrystallization: Engineering a Remedy for Caffeine Hydration
Crystal Growth & Design · 2005 · 649 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.