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Characterization of the Cellular Reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): Subcellular Localization, Substrate Dependence, and Involvement of Mitochondrial Electron Transport in MTT Reduction

Archives of Biochemistry and Biophysics · 1993 · Vol. 303(2) · pp. 474–482

Michael V. Berridge✉(Malaghan Institute of Medical Research)An S. Tan(Malaghan Institute of Medical Research)

Synthesis of Tetrazole Derivatives Quinazolinone synthesis and applications Synthesis and Characterization of Heterocyclic CompoundsMTT assayFormazanChemistryBiochemistryRotenoneSuccinate dehydrogenaseRespiratory chainMitochondrial respiratory chainBromideMitochondrion

MeSH terms

AnimalsAntimycin ABone MarrowCell LineChloromercuribenzoatesChlorpromazineCytochrome c GroupElectron Transport Complex IVColoring AgentsElectron TransportLysosomesMice, Inbred C3HMitochondriaNADNADP

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1,407

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