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Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

Immunity · 2013 · Vol. 38(4) · pp. 792–804

Daigo Hashimoto(Icahn School of Medicine at Mount Sinai)Andrew Chow(Albert Einstein College of Medicine)Clara Noizat(Sorbonne Université)Pearline Teo(Agency for Science, Technology and Research)Mary Beth Beasley(Icahn School of Medicine at Mount Sinai)Marylène Leboeuf(Icahn School of Medicine at Mount Sinai)Christian Becker(Icahn School of Medicine at Mount Sinai)Peter See(Agency for Science, Technology and Research)Jeremy Price(Icahn School of Medicine at Mount Sinai)Daniel Lucas(Albert Einstein College of Medicine)Melanie Greter(University of Zurich)Arthur Mortha(Icahn School of Medicine at Mount Sinai)Scott W. Boyer(University of California, Santa Cruz)Camilla Forsberg(University of California, Santa Cruz)Masato Tanaka(Tokyo University of Pharmacy and Life Sciences)Nico van Rooijen(Vrije Universiteit Amsterdam)Adolfo Garcı́a-Sastre(Icahn School of Medicine at Mount Sinai)E. Richard Stanley(Albert Einstein College of Medicine)Florent Ginhoux(Agency for Science, Technology and Research)Paul S. Frenette(Albert Einstein College of Medicine)Miriam Mérad✉(Icahn School of Medicine at Mount Sinai)

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Immune cells in cancer Neuroinflammation and Neurodegeneration Mechanisms Tryptophan and brain disordersBiologyMonocyteImmunologyMacrophageGenetics

MeSH terms

AdultAnimalsCell SurvivalCells, CulturedHomeostasisHumansLungMacrophagesMice, Mutant StrainsParabiosisInterleukin-4Bone Marrow TransplantationMacrophage Colony-Stimulating FactorGranulocyte-Macrophage Colony-Stimulating FactorReceptors, Granulocyte-Macrophage Colony-Stimulating Factor