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Evidence for a relation between metabolic derangements and increased levels of inflammatory mediators in a subgroup of patients with chronic obstructive pulmonary disease.

Thorax · 1996 · Vol. 51(8) · pp. 819–824
Annemie ScholsWim A. BuurmanA. J. Staal van den BrekelMieke A. DentenerEmiel F.�M. Wouters

Abstract

A subset of patients with COPD with an increased REE and decreased FFM have increased levels of acute phase reactant proteins and inflammatory cytokines in their serum; these phenomena may be causally related.

Respiratory Support and MechanismsChronic Obstructive Pulmonary Disease (COPD) ResearchBody Composition Measurement TechniquesMedicineCOPDBioelectrical impedance analysisInternal medicineC-reactive proteinBody mass indexResting energy expenditureGastroenterologyTumor necrosis factor alphaEndocrinology

MeSH terms

Lipopolysaccharide-Binding ProteinAcute-Phase ProteinsBody CompositionC-Reactive ProteinCarrier ProteinsEnergy MetabolismEnzyme-Linked Immunosorbent AssayHumansLungLung Diseases, ObstructiveMembrane GlycoproteinsMiddle AgedTumor Necrosis Factor-alphaAntigens, CDInterleukin-6

Funding

  • Incyte
Citations
523
FWCI
10.21
field-weighted impact
References
42
Percentile
98%
vs. same field & year
Citations per year
References
A biometric study of basal metabolism in man
Bulletin of Miscellaneous Information (Royal Gardens Kew) · 2014 · 1,864 citations
Creatinine assay by a reaction-kinetic principle
Clinica Chimica Acta · 1972 · 651 citations
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