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A Combined Transmembrane Topology and Signal Peptide Prediction Method

Journal of Molecular Biology · 2004 · Vol. 338(5) · pp. 1027–1036
Lukas KällAnders KroghErik L. L. Sonnhammer
Machine Learning in BioinformaticsRNA and protein synthesis mechanismsProtein Structure and DynamicsSignal peptideTransmembrane proteinTransmembrane domainMembrane proteinMembrane topologyTopology (electrical circuits)Peptide sequencePeptideProtein sequencingProteome

MeSH terms

Membrane ProteinsModels, MolecularProtein Structure, SecondaryProtein Sorting Signals

Funding

  • Pfizer
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References
A simple method for displaying the hydropathic character of a protein
Journal of Molecular Biology · 1982 · 22,952 citations
Patterns of Amino Acids near Signal‐Sequence Cleavage Sites
European Journal of Biochemistry · 1983 · 2,292 citations
Hidden Markov Models in Computational Biology
Journal of Molecular Biology · 1994 · 1,947 citations
Membrane protein structure prediction
Journal of Molecular Biology · 1992 · 1,673 citations
Selection of representative protein data sets
Protein Science · 1992 · 823 citations
Transmembrane helices predicted at 95% accuracy
Protein Science · 1995 · 669 citations
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