article Open AccessTop 1% cited
Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy
PLoS Pathogens · 2014 · Vol. 10(11) · pp. e1004473–e1004473
Julian Elliott(Burnet Institute)Fiona Wightman(Monash University)Ajantha Solomon(Monash University)Khader Ghneim(Vaccine & Gene Therapy Institute of Florida)Jeffrey D. Ahlers(Vaccine & Gene Therapy Institute of Florida)Mark J. Cameron(Vaccine & Gene Therapy Institute of Florida)Miranda Z. Smith(Peter Doherty Institute)Tim Spelman(Burnet Institute)James McMahon(Monash University)Pushparaj Velayudham(Burnet Institute)Gregor J. Brown(Monash University)Janine Roney(Monash University)Jo Watson(National Association of People with HIV Australia)Miles H. Prince(University of Melbourne)Jennifer Hoy(Monash University)Nicolas Chomont(Vaccine & Gene Therapy Institute of Florida)Rémi Fromentin(Vaccine & Gene Therapy Institute of Florida)Francesco A. Procopio(Vaccine & Gene Therapy Institute of Florida)Joumana Zeidan(Vaccine & Gene Therapy Institute of Florida)Sarah Palmer(University of Sydney)Lina Odevall(Karolinska Institutet)Ricky W. Johnstone(Peter MacCallum Cancer Centre)Ben P. Martin(University of Melbourne)Elizabeth Sinclair(University of California, San Francisco)Steven G. Deeks(University of California, San Francisco)Daria J. Hazuda(United States Military Academy)Paul Cameron(University of Melbourne)Rafick‐Pierre Sékaly(Vaccine & Gene Therapy Institute of Florida)Sharon R. Lewin✉(Peter Doherty Institute)
Abstract
ClinicalTrials.gov NCT01365065.
HIV Research and TreatmentHIV/AIDS drug development and treatmentHIV/AIDS Research and InterventionsVorinostatVirus latencyHistone deacetylaseHistone deacetylase inhibitorRNATranscription (linguistics)Viral loadVirologyReverse transcriptaseVirus
MeSH terms
VorinostatAdultFemaleHumansHydroxamic AcidsLymphocyte ActivationMaleMiddle AgedRNA, ViralTranscription, GeneticVirus ActivationCD4-Positive T-LymphocytesHIV-1HIV InfectionsVirus Latency
Funding
- Bristol-Myers Squibb
- Gilead Sciences
- Delaney AIDS Research Enterprise
- Burnet Institute
- ViiV Healthcare
- National Institutes of Health
- Medical Research Council
- National Health and Medical Research Council
- Cilag
Citations
509
FWCI
23.67
field-weighted impact
References
61
Percentile
100%
vs. same field & year
Citations per year
Cited by
The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo
PLoS Pathogens · 2015 · 519 citations
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