article Open AccessTop 1% cited
Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process
BMC Cancer · 2007 · Vol. 7(1) · pp. 64–64
Uma Chandran✉(University of Pittsburgh)Changqing Ma(University of Pittsburgh)Rajiv Dhir(University of Pittsburgh)Michelle Bisceglia(University of Pittsburgh)Maureen A. Lyons‐Weiler(University of Pittsburgh)Wenjing Liang(University of Pittsburgh)George K. Michalopoulos(University of Pittsburgh)Michael J. Becich(University of Pittsburgh)Federico A. Monzon(University of Pittsburgh)
Abstract
We hypothesize that these genes have a role in the biology of metastatic disease and that they represent potential therapeutic targets for prostate cancer.
Prostate Cancer Treatment and ResearchBone health and treatmentsMolecular Biology Techniques and ApplicationsProstate cancerMetastasisCancer researchProstateGene expression profilingStromal cellBiologySurgical oncologyTranscriptomeGene expression
MeSH terms
HumansMaleNeoplasm MetastasisProstatic NeoplasmsGene ExpressionStromal CellsGenetic Heterogeneity
Funding
- Pennsylvania Department of Health
- National Institutes of Health
- National Cancer Institute
Citations
509
FWCI
13.19
field-weighted impact
References
49
Percentile
99%
vs. same field & year
Citations per year
References
A multigenic program mediating breast cancer metastasis to bone
Cancer Cell · 2003 · 2,589 citations
Molecular determinants of resistance to antiandrogen therapy
Nature Medicine · 2003 · 2,266 citations
Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance
American Journal Of Pathology · 2004 · 571 citations
Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer
Cancer Research · 2006 · 1,074 citations
Cluster analysis and display of genome-wide expression patterns
Proceedings of the National Academy of Sciences · 1998 · 16,353 citations
Gene expression correlates of clinical prostate cancer behavior
Cancer Cell · 2002 · 2,523 citations
Significance analysis of microarrays applied to the ionizing radiation response
Proceedings of the National Academy of Sciences · 2001 · 10,653 citations
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