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Association of Hyperglycemia with Increased Mortality after Severe Burn Injury

Dennis C. GoreDavid L. ChinkesJohn P. HeggersDavid N. HerndonSteven E. WolfManubdai Desai

Abstract

This association between poor glucose control, bacteremia/fungemia, reduced skin graft take, and subsequent mortality in severely burned children may be related to a hyperglycemia-induced detriment in antimicrobial defense. Although this report fails to establish cause and effect, these findings suggest that aggressive maneuvers to normalize plasma glucose in critically injured patients may be warranted.

Burn Injury Management and OutcomesWound Healing and TreatmentsDiabetic Foot Ulcer Assessment and ManagementMedicineTotal body surface areaInternal medicineIncidence (geometry)Diabetes mellitusFungemiaGastroenterologyBlood sugarBacteremiaSurgery

MeSH terms

BurnsEnergy IntakeChildHumansHyperglycemiaInsulinLength of StaySeverity of Illness IndexGrowth HormoneBacteremia
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