article Open AccessTop 10% cited
Evolutionary conservation of codon optimality reveals hidden signatures of cotranslational folding
Nature Structural & Molecular Biology · 2012 · Vol. 20(2) · pp. 237–243
Sebastian Pechmann(Stanford University)Judith Frydman✉(Stanford University)
RNA and protein synthesis mechanismsRNA modifications and cancerGenomics and Phylogenetic StudiesCodon usage biasTranslation (biology)Folding (DSP implementation)BiologyProtein foldingTranslational efficiencyComputational biologyFunction (biology)Saccharomyces cerevisiaeTransfer RNA
MeSH terms
Amino Acid SequenceCodonKineticsModels, MolecularMolecular Sequence DataRNA, TransferSpecies SpecificityProtein BiosynthesisYeastsProtein Structure, SecondaryProtein FoldingMyosin Light ChainsEvolution, MolecularSaccharomyces cerevisiae Proteins
Funding
- European Molecular Biology Organization
- Francis Crick Institute
- National Institutes of Health
Citations
527
FWCI
10.34
field-weighted impact
References
51
Percentile
99%
vs. same field & year
Citations per year
References
Synonymous but not the same: the causes and consequences of codon bias
Nature Reviews Genetics · 2010 · 1,743 citations
Transient ribosomal attenuation coordinates protein synthesis and co-translational folding
Nature Structural & Molecular Biology · 2009 · 561 citations
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
Nucleic Acids Research · 1994 · 64,626 citations
Global Transcriptional Responses of Fission Yeast to Environmental Stress
Molecular Biology of the Cell · 2003 · 810 citations
tRNAscan-SE: A Program for Improved Detection of Transfer RNA Genes in Genomic Sequence
Nucleic Acids Research · 1997 · 11,100 citations
Protein secondary structure prediction based on position-specific scoring matrices 1 1Edited by G. Von Heijne
Journal of Molecular Biology · 1999 · 5,511 citations
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