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Perturbations of the AKT signaling pathway in human cancer

Oncogene · 2005 · Vol. 24(50) · pp. 7455–7464
Deborah A. AltomareJoseph R. Testa
PI3K/AKT/mTOR signaling in cancerUbiquitin and proteasome pathwaysCancer Mechanisms and TherapyProtein kinase BBiologyPTENPI3K/AKT/mTOR pathwaySignal transductionCancer researchAKT2KinaseCell biologyProto-Oncogene Proteins c-akt

MeSH terms

Cell SurvivalCell Transformation, NeoplasticHumansMutationNeoplasm InvasivenessNeoplasmsNeovascularization, PathologicProtein KinasesSignal TransductionGenes, Tumor SuppressorGenetic Predisposition to DiseaseCell ProliferationProto-Oncogene Proteins c-aktTOR Serine-Threonine Kinases

Funding

  • National Institutes of Health
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