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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

Nature Genetics · 2006 · Vol. 38(3) · pp. 320–323

Struan F.A. Grant✉(deCODE Genetics (Iceland))Guðmar Þorleifsson(deCODE Genetics (Iceland))Inga Reynisdóttir(deCODE Genetics (Iceland))Rafn Benediktsson(National University Hospital of Iceland)Andrei Manolescu(deCODE Genetics (Iceland))Jesús Sainz(deCODE Genetics (Iceland))Agnar Helgason(deCODE Genetics (Iceland))Hreinn Stefánsson(deCODE Genetics (Iceland))Valur Emilsson(deCODE Genetics (Iceland))Anna Helgadóttir(deCODE Genetics (Iceland))Unnur Styrkársdóttir(deCODE Genetics (Iceland))Kristinn P. Magnússon(deCODE Genetics (Iceland))G. Bragi Walters(deCODE Genetics (Iceland))Ebba Pálsdóttir(deCODE Genetics (Iceland))Þorbjörg Jónsdóttir(deCODE Genetics (Iceland))Thorunn Gudmundsdottir(deCODE Genetics (Iceland))Arnaldur Gylfason(deCODE Genetics (Iceland))Jona Saemundsdottir(deCODE Genetics (Iceland))Robert L. Wilensky(University of Pennsylvania)Muredach P. Reilly(University of Pennsylvania)Daniel J. Rader(University of Pennsylvania)Yu Z. Bagger(Center for Clinical & Basic Research)Claus Christiansen(Center for Clinical & Basic Research)Vilmundur Guðnason(Icelandic Heart Association)Gunnar Sigurðsson(Icelandic Heart Association)Unnur Þorsteinsdóttir(deCODE Genetics (Iceland))Jeffrey R. Gulcher(deCODE Genetics (Iceland))Augustine Kong(deCODE Genetics (Iceland))Kāri Stefánsson(deCODE Genetics (Iceland))

View via DOI Publisher page

Genetics and Neurodevelopmental Disorders Cancer-related gene regulation Pancreatic function and diabetesTCF7L2BiologyTCF4GeneticsPopulationGlucose homeostasisAlleleTranscription factorType 2 diabetesMicrosatellite

MeSH terms

Chromosome MappingChromosomes, Human, Pair 10DenmarkDiabetes Mellitus, Type 2Gene FrequencyGenetic Carrier ScreeningHumansIntronsMolecular Sequence DataReference ValuesCohort StudiesMicrosatellite RepeatsGenetic Predisposition to DiseaseTCF Transcription FactorsTranscription Factor 7-Like 2 Protein