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Endogenous Bile Acids Are Ligands for the Nuclear Receptor FXR/BAR
Molecular Cell · 1999 · Vol. 3(5) · pp. 543–553
Haibo Wang✉Jasmine Chen(Beckman Research Institute)Kevin Hollister(Beckman Research Institute)Lawrence C. Sowers(City Of Hope National Medical Center)Barry M. Forman(Beckman Research Institute)
Drug Transport and Resistance MechanismsCholesterol and Lipid MetabolismPeroxisome Proliferator-Activated ReceptorsBiologyNuclear receptorFarnesoid X receptorEndogenyReceptorG protein-coupled bile acid receptorCell biologyBar (unit)BiochemistryTranscription factor
MeSH terms
Receptor, Farnesoid X-ActivatedAnimalsBileBile Acids and SaltsCattleCells, CulturedChenodeoxycholic AcidCholesterolDNA-Binding ProteinsDose-Response Relationship, DrugHomeostasisHumansLigandsRecombinant ProteinsSwine
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References
Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay
Molecular Endocrinology · 1997 · 1,181 citations
Nuclear receptor coactivators
Current Opinion in Cell Biology · 1997 · 717 citations
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