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Memantine for dementia

Cochrane Database of Systematic Reviews · 2006 · Vol. 3(2) · pp. CD003154–CD003154
Rupert McShaneAlmudena Areosa SastreNeda Minakaran

Abstract

Memantine has a small beneficial effect at six months in moderate to severe AD. In patients with mild to moderate dementia, the small beneficial effect on cognition was not clinically detectable in those with vascular dementia and was detectable in those with AD. Memantine is well tolerated.

Neurological Disease Mechanisms and TreatmentsDiet and metabolism studiesNeurological Disorders and TreatmentsMemantineDementiaMedicineClinical trialVascular dementiaRandomized controlled trialPlaceboInternal medicineDiseaseAlternative medicine

MeSH terms

Activities of Daily LivingAgedAged, 80 and overAlzheimer DiseaseCognition DisordersDementiaHumansMemantineDementia, VascularRandomized Controlled Trials as TopicExcitatory Amino Acid Antagonists
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