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Infections caused by KPC-producing <i>Klebsiella pneumoniae</i> : differences in therapy and mortality in a multicentre study
Journal of Antimicrobial Chemotherapy · 2015 · Vol. 70(7) · pp. 2133–2143
Mario Tumbarello✉(Università Cattolica del Sacro Cuore)Enrico Maria Trecarichi(Università Cattolica del Sacro Cuore)Francesco Giuseppe De Rosa(University of Turin)Maddalena Giannella(Policlinico S.Orsola-Malpighi)Daniele Roberto Giacobbe(Istituti di Ricovero e Cura a Carattere Scientifico)Matteo Bassetti(Ospedale Santa Maria della Misericordia di Udine)Angela Raffaella Losito(Università Cattolica del Sacro Cuore)Michele Bartoletti(University of Bologna)Valerio Del Bono(Istituti di Ricovero e Cura a Carattere Scientifico)Silvia Corcione(Ospedale Amedeo di Savoia)G. Maiuro(Università Cattolica del Sacro Cuore)Sara Tedeschi(Policlinico S.Orsola-Malpighi)Luigi Celani(Università Cattolica del Sacro Cuore)Chiara Simona Cardellino(Ospedale Amedeo di Savoia)Teresa Spanu(Università Cattolica del Sacro Cuore)Anna Marchese(University of Genoa)Simone Ambretti(Policlinico S.Orsola-Malpighi)Roberto Cauda(Università Cattolica del Sacro Cuore)Claudio Viscoli(University of Genoa)Pierluigi Viale(University of Bologna)on behalf of ISGRI-SITA (Italian Study Group on Resistant Infections of the Società Italiana Terapia Antinfettiva)
Abstract
KPC-Kp infections are associated with high mortality. Treatment with two or more drugs displaying activity against the isolate improves survival, mainly in patients who are critically ill.
Antibiotic Resistance in BacteriaPneumonia and Respiratory InfectionsAntibiotics Pharmacokinetics and EfficacyMedicineInternal medicineSeptic shockKlebsiella pneumoniaeRetrospective cohort studyMortality rateCohortRespiratory tract infectionsSepsisRespiratory system
MeSH terms
AdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesFemaleHospitals, TeachingHumansItalyKlebsiella InfectionsKlebsiella pneumoniaeMaleMicrobial Sensitivity Tests
Citations
506
FWCI
20.49
field-weighted impact
References
38
Percentile
100%
vs. same field & year
Citations per year
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