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Exosomes/microvesicles from induced pluripotent stem cells deliver cardioprotective miRNAs and prevent cardiomyocyte apoptosis in the ischemic myocardium

International Journal of Cardiology · 2015 · Vol. 192 · pp. 61–69
Yingjie WangLan ZhangYongjun LiLijuan ChenXiaolong WangWei GuoXue ZhangGangjian QinSheng-hu HeArthur D. ZimmermanYutao LiuIl‐man KimNeal L. WeintraubYaoliang Tang
Extracellular vesicles in diseaseMicroRNA in disease regulationRNA Interference and Gene DeliveryMicrovesiclesInduced pluripotent stem cellCardioprotectionCell biologyExosomeMedicineApoptosisStem cellHomeobox protein NANOGmicroRNA

MeSH terms

AnimalsCells, CulturedFibroblastsMyocardial Reperfusion InjuryMyocardial IschemiaApoptosisMyocytes, CardiacMicroRNAsMiceCell-Derived MicroparticlesExosomesInduced Pluripotent Stem Cells

Funding

  • National Natural Science Foundation of China
  • Science and Technology Commission of Shanghai Municipality
  • National Institutes of Health
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