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Systematic Interindividual Differences in Neurobehavioral Impairment from Sleep Loss: Evidence of Trait-Like Differential Vulnerability

SLEEP · 2004 · Vol. 27(3) · pp. 423–33
Hans P. A. Van DongenMaurice D. BaynardGreg MaislinDavid F. Dinges

Abstract

Neurobehavioral deficits from sleep loss varied significantly among individuals and were stable within individuals. Interindividual differences in neurobehavioral responses to sleep deprivation were not merely a consequence of variations in sleep history. Rather, they involved trait-like differential vulnerability to impairment from sleep loss, for which neurobiologic correlates have yet to be discovered.

Sleep and Work-Related FatigueSleep and related disordersErgonomics and Musculoskeletal DisordersSleep deprivationSleep restrictionSleep (system call)Sleep debtWakefulnessPsychologyAudiologySlow-wave sleepMedicineCircadian rhythm

MeSH terms

Adaptation, PsychologicalAdultBrainCognition DisordersFemaleHumansMalePsychomotor PerformanceSurveys and QuestionnairesSleep DeprivationWakefulnessCluster AnalysisPolysomnography

Funding

  • National Aeronautics and Space Administration
  • National Institutes of Health
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