article Open AccessTop 1% cited
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
Nature Immunology · 2000 · Vol. 1(5) · pp. 398–401
Evelyn A. Kurt‐Jones✉(Dana-Farber Cancer Institute)L. Popova(Harvard University)Laura Kwinn(Dana-Farber Cancer Institute)Lia M. Haynes(Centers for Disease Control and Prevention)Les Jones(National Center for Infectious Diseases)Ralph A. Tripp(National Center for Infectious Diseases)Edward E. Walsh(University of Rochester)Mason W. Freeman(Massachusetts General Hospital)Douglas T. Golenbock(Boston University)Larry J. Anderson(Centers for Disease Control and Prevention)Robert W. Finberg(University of Massachusetts Chan Medical School)
Respiratory viral infections researchImmune Response and InflammationPneumonia and Respiratory InfectionsPattern recognition receptorInnate immune systemBiologyCD14ReceptorImmune systemTLR4ImmunologyImmune receptorToll-like receptor
MeSH terms
AnimalsAntibodies, MonoclonalHumansLeukocytes, MononuclearLungMembrane GlycoproteinsReceptors, Cell SurfaceRespiratory Syncytial VirusesViral Fusion ProteinsCytokinesMice, KnockoutRespiratory Syncytial Virus InfectionsInflammation MediatorsLipopolysaccharide ReceptorsDrosophila Proteins
Funding
- National Institutes of Health
Citations
1,662
FWCI
48.80
field-weighted impact
References
42
Percentile
100%
vs. same field & year
Citations per year
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References
Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the <i>Lps</i> Gene Product
The Journal of Immunology · 1999 · 3,357 citations
Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction
Journal of Biological Chemistry · 1999 · 1,956 citations
Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components
Immunity · 1999 · 3,351 citations
MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4
The Journal of Experimental Medicine · 1999 · 2,181 citations
Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (<i>Tlr4</i>)
The Journal of Experimental Medicine · 1999 · 1,535 citations
Cutting Edge: Recognition of Gram-Positive Bacterial Cell Wall Components by the Innate Immune System Occurs Via Toll-Like Receptor 2
The Journal of Immunology · 1999 · 1,233 citations
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