Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
Chromatin Remodeling and Cancer
This cluster of papers focuses on the role of chromatin remodeling, particularly the SWI/SNF complexes and ARID1A mutations, in cancer development and progression. It explores the impact of these mutations on epigenetic regulation, tumor suppression, genomic analysis, oncogenic transformation, and synthetic lethality. Additionally, it delves into the involvement of chromatin remodeling in mammalian development.
20K works worldwide333.5K citations
Chromatin RemodelingSWI/SNF ComplexesARID1A MutationsCancerEpigeneticsTumor SuppressorGenomic AnalysisOncogenic TransformationSynthetic LethalityMammalian Development
