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Takumi Ito

Tokyo Medical UniversityORCID https://orcid.org/0000-0002-9997-2664

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Impact (2-yr)

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Top Publications

Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

Leukemia2012790 citations

Immunomodulatory agents lenalidomide and pomalidomide co‐stimulate <scp>T</scp> cells by inducing degradation of <scp>T</scp> cell repressors <scp>I</scp> karos and <scp>A</scp> iolos via modulation of the <scp>E</scp> 3 ubiquitin ligase complex <scp>CRL</scp> 4 <scp> <sup>CRBN</sup> </scp>

British Journal of Haematology2013615 citations

Takumi Ito · Scinovex