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Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

European Journal of Medicinal Chemistry · 2015 · Vol. 101 · pp. 476–495
Anuradha ThakurRamit SinglaVikas Jaitak
Synthesis and biological activityClick Chemistry and ApplicationsSynthesis and Biological EvaluationChemistryCoumarinMechanism of actionMechanism (biology)Computational biologyStructure–activity relationshipCombinatorial chemistryPharmacologyStereochemistryBiochemistry

MeSH terms

Antineoplastic AgentsCoumarinsDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansNeoplasmsProtein KinasesStructure-Activity RelationshipMolecular StructureProtein Kinase InhibitorsCell Proliferation
Citations
476
FWCI
22.83
field-weighted impact
References
113
Percentile
100%
vs. same field & year
Citations per year
References
Coumarin hybrids as novel therapeutic agents
Bioorganic & Medicinal Chemistry · 2014 · 289 citations
Review on Natural Coumarin Lead Compounds for Their Pharmacological Activity
BioMed Research International · 2013 · 905 citations
A review on coumarins as acetylcholinesterase inhibitors for Alzheimer’s disease
Bioorganic & Medicinal Chemistry · 2011 · 520 citations
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